Effects of Selegiline in a retroviral rat model for neurodegenerative disease

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Effects of Selegiline in a retroviral rat model for neurodegenerative disease.

Upon inoculation into neonatal rats, murine leukemia virus (MuLV) NT40 causes a non-inflammatory degeneration of the central nervous system. While microglia cells appear to be the major target cells within the brain parenchyma for neurovirulent MuLV, degenerating neurons do not express retroviral gene products. In order to protect rats from neuronal damage we treated retrovirally infected rats ...

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ژورنال

عنوان ژورنال: Journal of Neurovirology

سال: 1999

ISSN: 1355-0284,1538-2443

DOI: 10.3109/13550289909045374